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South America

🇵🇾 Vaccines for Paraguay

Entry requirements & recommendations for travel to Paraguay

Paraguay requires Yellow Fever proof if arriving from an endemic country, and recommends it for travel outside Asunción, particularly to jungle border areas. Malaria risk is limited to border areas. Hepatitis A and Typhoid are recommended generally. Dengue is widespread throughout the country, including Asunción, and is the more relevant practical mosquito-borne consideration for most visitors than malaria. Paraguay is one of the less-visited South American countries for tourism, with Asunción and the Jesuit mission ruins (a UNESCO site) being notable attractions, alongside the Chaco region for those interested in remote wilderness. Healthcare in Asunción is reasonable for routine needs; rural areas have more limited facilities.

Medical disclaimer: This is general information only — not personal medical advice. Requirements and risks change. Always consult a qualified travel health clinic before departure.
Required for entry
Yellow Fever
Certificate required if arriving from endemic country. Recommended for travel outside Asunción.
💉 1 dose (lifetime)
📅 Book at least 3 weeks before travel
⚡ Effective: 10 days after vaccination. Certificate valid for life.
🛡 Protects for: Lifetime (single dose).
Required for entry
Recommended by WHO & CDC
Hepatitis A
Food and water contamination risk.
💉 2 doses
📅 Book at least 4 weeks before travel
⚡ Effective: 2 weeks after 1st dose. Full protection after 2nd dose (6–12 months later).
🛡 Protects for: 1st dose ~1 yr. 2nd dose: lifetime.
Recommended
Typhoid
Contaminated food and water.
💉 1 dose
📅 Book at least 3 weeks before travel
⚡ Effective: 2 weeks after vaccination.
🛡 Protects for: 3–5 years. Booster recommended if re-exposure.
Recommended
Disease risks
  • ⚠Malaria (limited — border areas)
  • ⚠Dengue (widespread)
  • ⚠Yellow Fever (jungle border areas)
  • ⚠Leishmaniasis (rural)
Approximate cost per person
Required vaccines
~€74
(~$81)
per person · full courses
Yellow Fever (1 dose)€74 ($81)
Recommended vaccines
~€249
(~$271)
per person · full courses
Hepatitis A (2 doses)€140 ($152)
Typhoid (1 dose)€45 ($49)
Malaria tablets (4 weeks) (1 dose)€64 ($70)

💡 Approximate figures based on private European travel clinic rates (April 2026). Actual costs vary by clinic and country. Not all recommended vaccines will apply to every trip — discuss your specific itinerary with a travel health clinic.

Often combined with
BrazilColombiaPeruVenezuela
Common questions
Do I need vaccines for Paraguay?
Yellow Fever proof is required if arriving from an endemic country, and recommended for travel outside Asunción, particularly jungle border areas. Hepatitis A and Typhoid are recommended generally.
Is there malaria in Paraguay?
Malaria risk is limited to border areas of Paraguay. Asunción and the main tourist circuit, including the Jesuit mission ruins, carry low malaria risk, though dengue is a more relevant practical concern — see the main health risk question.
Is tap water safe in Paraguay?
Tap water in Asunción is generally treated and considered reasonably safe, though bottled water is also commonly used. In rural areas, bottled water is a sensible precaution.
What is the main health risk in Paraguay?
Dengue is widespread throughout Paraguay, including Asunción, and is the most relevant practical mosquito-borne risk for most visitors — more so than malaria, which is confined to border areas. There is no widely available vaccine for most travellers — mosquito repellent is the main prevention, alongside the general Hepatitis A and Typhoid precautions for food and water.