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South America

🇵🇪 Vaccines for Peru

Entry requirements & recommendations for travel to Peru

Hepatitis A and Typhoid recommended. Yellow Fever is recommended and required for jungle regions in the Amazon — not needed for Lima, Cusco, or Machu Picchu. Malaria risk in the jungle lowlands. Altitude sickness is a practical concern for most visitors heading to Cusco and the Sacred Valley.

Medical disclaimer: This is general information only — not personal medical advice. Requirements and risks change. Always consult a qualified travel health clinic before departure.
Required for entry

No vaccines required for entry to this destination.

Recommended by WHO & CDC
Hepatitis A
Food and water contamination risk.
💉 2 doses
📅 Book at least 4 weeks before travel
⚡ Effective: 2 weeks after 1st dose. Full protection after 2nd dose (6–12 months later).
🛡 Protects for: 1st dose ~1 yr. 2nd dose: lifetime.
Recommended
Typhoid
Contaminated food and water.
💉 1 dose
📅 Book at least 3 weeks before travel
⚡ Effective: 2 weeks after vaccination.
🛡 Protects for: 3–5 years. Booster recommended if re-exposure.
Recommended
Rabies
Animal bites risk.
💉 3 doses
📅 Book at least 5 weeks before travel
⚡ Effective: After 3rd dose. 2nd dose 7 days after 1st, 3rd dose 21 days after 1st.
🛡 Protects for: Pre-exposure reduces post-bite treatment needed. Boosters based on blood tests.
Recommended
Yellow Fever
Recommended for Amazon jungle areas — not Lima or Machu Picchu.
💉 1 dose (lifetime)
📅 Book at least 3 weeks before travel
⚡ Effective: 10 days after vaccination. Certificate valid for life.
🛡 Protects for: Lifetime (single dose).
Recommended
Disease risks
  • ⚠Malaria (Amazon lowlands — not Lima, Cusco, Machu Picchu or Inca Trail at altitude)
  • ⚠Dengue (Amazon and coastal lowlands)
  • ⚠Yellow Fever (Amazon jungle areas)
  • ⚠Altitude sickness (Cusco, Machu Picchu, Lake Titicaca)
  • ⚠Leishmaniasis (jungle)
Notes: No malaria or Yellow Fever risk in Lima, Cusco or Machu Picchu. Malaria prophylaxis and Yellow Fever vaccine for Amazon/jungle areas. Hepatitis A and Typhoid recommended throughout.
Approximate cost per person
Required vaccines
—
None required for entry
Recommended vaccines
~€596
(~$649)
per person · full courses
Hepatitis A (2 doses)€140 ($152)
Typhoid (1 dose)€45 ($49)
Rabies (3 doses)€273 ($297)
Yellow Fever (1 dose)€74 ($81)
Malaria tablets (4 weeks) (1 dose)€64 ($70)

💡 Approximate figures based on private European travel clinic rates (April 2026). Actual costs vary by clinic and country. Not all recommended vaccines will apply to every trip — discuss your specific itinerary with a travel health clinic.

Often combined with
BrazilColombiaBoliviaEcuador
When to book

Book 4–6 weeks before travel. Yellow Fever vaccination must be done at least 10 days before entering risk areas as the certificate is only valid after 10 days. Hepatitis A and Typhoid can be done 2–3 weeks before departure. Malaria tablets need to start before entering risk areas.

Common questions
Do I need Yellow Fever vaccine for Peru?
It depends on your itinerary. Yellow Fever is recommended and required if visiting Amazon jungle regions in Peru. It is not required or recommended for Lima, Cusco, Machu Picchu, the Sacred Valley, or the Inca Trail. If you are flying between Lima and Iquitos or visiting the Amazon basin, vaccination is essential.
Is there malaria in Peru?
Malaria risk in Peru is concentrated in the Amazon basin — the Loreto, Ucayali, and Madre de Dios regions. There is no malaria risk in Lima, Cusco, the Inca Trail, or Machu Picchu. If your itinerary includes the Amazon, antimalarials are recommended.
Do I need vaccines for Machu Picchu?
No vaccines are required for Machu Picchu. Hepatitis A and Typhoid are recommended. The main health concern for the Cusco and Machu Picchu region is altitude sickness — Cusco sits at 3,400m and altitude acclimatisation is important.
How do I prevent altitude sickness in Peru?
Acclimatise by spending 1–2 days in Cusco before ascending further. Avoid alcohol and heavy exertion on arrival. Diamox (acetazolamide) is a prescription medication that can help — discuss it with your doctor before travel. Most people experience some symptoms; most adjust within 24–48 hours.

Data based on WHO International Travel and Health and CDC Yellow Book 2026. Last verified: May 2026. Always verify current requirements with a travel health clinic before departure.