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South America

🇧🇷 Vaccines for Brazil

Entry requirements & recommendations for travel to Brazil

Brazil requires Yellow Fever vaccination for travel to the Amazon region and is recommended for most areas outside the immediate coastal strip around Rio de Janeiro and São Paulo — some Brazilian states require proof of vaccination depending on your itinerary. Rio itself sits in a recommended zone in some guidance, so check current requirements based on your specific stops. Malaria risk is confined to the Amazon basin, not Rio, São Paulo, or the main coastal tourist areas. Dengue, however, is a significant risk throughout the country including Rio, with outbreaks occurring even in major cities. Hepatitis A and Typhoid are recommended generally. Healthcare in Rio and São Paulo is good; the Amazon region has much more limited access.

Medical disclaimer: This is general information only — not personal medical advice. Requirements and risks change. Always consult a qualified travel health clinic before departure.
Required for entry
Yellow Fever
Required for travel to Amazon/jungle areas. Some states require certificate. Recommended for areas outside large coastal cities.
💉 1 dose (lifetime)
📅 Book at least 3 weeks before travel
⚡ Effective: 10 days after vaccination. Certificate valid for life.
🛡 Protects for: Lifetime (single dose).
Required for entry
Recommended by WHO & CDC
Hepatitis A
Food and water contamination risk.
💉 2 doses
📅 Book at least 4 weeks before travel
⚡ Effective: 2 weeks after 1st dose. Full protection after 2nd dose (6–12 months later).
🛡 Protects for: 1st dose ~1 yr. 2nd dose: lifetime.
Recommended
Typhoid
Contaminated food and water risk.
💉 1 dose
📅 Book at least 3 weeks before travel
⚡ Effective: 2 weeks after vaccination.
🛡 Protects for: 3–5 years. Booster recommended if re-exposure.
Recommended
Rabies
Animal bites risk, especially in rural areas.
💉 3 doses
📅 Book at least 5 weeks before travel
⚡ Effective: After 3rd dose. 2nd dose 7 days after 1st, 3rd dose 21 days after 1st.
🛡 Protects for: Pre-exposure reduces post-bite treatment needed. Boosters based on blood tests.
Recommended
Disease risks
  • ⚠Malaria (Amazon basin — not Rio de Janeiro, São Paulo, coastal cities)
  • ⚠Dengue (widespread including urban areas)
  • ⚠Zika
  • ⚠Yellow Fever (Amazon/jungle areas)
  • ⚠Chikungunya
Notes: Yellow Fever strongly recommended for Amazon/jungle travel — required by some states. No malaria risk in Rio, São Paulo or coastal tourist areas. Malaria prophylaxis for Amazon basin. Dengue is a significant risk throughout including Rio.
Approximate cost per person
Required vaccines
~€74
(~$81)
per person · full courses
Yellow Fever (1 dose)€74 ($81)
Recommended vaccines
~€522
(~$568)
per person · full courses
Hepatitis A (2 doses)€140 ($152)
Typhoid (1 dose)€45 ($49)
Rabies (3 doses)€273 ($297)
Malaria tablets (4 weeks) (1 dose)€64 ($70)

💡 Approximate figures based on private European travel clinic rates (April 2026). Actual costs vary by clinic and country. Not all recommended vaccines will apply to every trip — discuss your specific itinerary with a travel health clinic.

Often combined with
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Common questions
Do I need Yellow Fever vaccine for Brazil?
Required for the Amazon region, and recommended for most of Brazil outside a narrow coastal strip — check current guidance for your specific itinerary, as Rio de Janeiro sits close to this boundary in some recommendations and requirements can vary by which Brazilian states you'll visit, including connections through Brazil to other South American countries.
Is there malaria in Brazil?
Malaria risk is confined to the Amazon basin region. Rio de Janeiro, São Paulo, and the main coastal tourist areas carry no malaria risk. If your itinerary includes Amazon lodges or river travel, discuss antimalarial medication with a travel clinic.
What vaccines do I need for Rio de Janeiro?
Hepatitis A and Typhoid are recommended generally. Yellow Fever guidance for Rio specifically can vary — check current recommendations as Rio sits near the boundary of zones where Yellow Fever is and isn't recommended. No malaria risk in Rio itself. Dengue is a real risk in Rio, including during major events like Carnival, so mosquito precautions matter.
Do I need vaccines for the Amazon in Brazil?
Yes — Yellow Fever vaccination is required for Amazon region travel, and malaria prophylaxis is recommended given the risk present throughout the basin. Hepatitis A and Typhoid are also relevant given more limited infrastructure outside major Amazon gateway cities like Manaus.