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East Africa

🇲🇬 Vaccines for Madagascar

Entry requirements & recommendations for travel to Madagascar

Yellow Fever required if arriving from endemic countries. Malaria is endemic and antimalarials are essential. Hepatitis A and Typhoid recommended. Plague occurs in some rural areas — unusual but worth knowing if travelling off the main routes.

Medical disclaimer: This is general information only — not personal medical advice. Requirements and risks change. Always consult a qualified travel health clinic before departure.
Required for entry

No vaccines required for entry to this destination.

Recommended by WHO & CDC
Hepatitis A
Food and water contamination risk.
💉 2 doses
📅 Book at least 4 weeks before travel
⚡ Effective: 2 weeks after 1st dose. Full protection after 2nd dose (6–12 months later).
🛡 Protects for: 1st dose ~1 yr. 2nd dose: lifetime.
Recommended
Typhoid
Contaminated food and water.
💉 1 dose
📅 Book at least 3 weeks before travel
⚡ Effective: 2 weeks after vaccination.
🛡 Protects for: 3–5 years. Booster recommended if re-exposure.
Recommended
Rabies
Animal bites risk.
💉 3 doses
📅 Book at least 5 weeks before travel
⚡ Effective: After 3rd dose. 2nd dose 7 days after 1st, 3rd dose 21 days after 1st.
🛡 Protects for: Pre-exposure reduces post-bite treatment needed. Boosters based on blood tests.
Recommended
Disease risks
  • ⚠Malaria (high risk throughout)
  • ⚠Plague (periodic outbreaks — highest in the world)
  • ⚠Rabies
  • ⚠Cholera (periodic)
Notes: Malaria prophylaxis essential. Madagascar has one of the highest rates of plague in the world — avoid contact with rodents and fleas.
Approximate cost per person
Required vaccines
—
None required for entry
Recommended vaccines
~€522
(~$568)
per person · full courses
Hepatitis A (2 doses)€140 ($152)
Typhoid (1 dose)€45 ($49)
Rabies (3 doses)€273 ($297)
Malaria tablets (4 weeks) (1 dose)€64 ($70)

💡 Approximate figures based on private European travel clinic rates (April 2026). Actual costs vary by clinic and country. Not all recommended vaccines will apply to every trip — discuss your specific itinerary with a travel health clinic.

Often combined with
KenyaTanzaniaEthiopiaUganda
When to book

Book 6–8 weeks before travel. Yellow Fever timing if arriving from endemic countries. Malaria tablets need to start before travel.

Common questions
Do I need vaccines for Madagascar?
Yellow Fever proof required if arriving from endemic countries. Malaria prevention is essential. Hepatitis A and Typhoid recommended. Plague occurs in some rural areas — unusual but notable.
Is there malaria in Madagascar?
Yes. Malaria is endemic throughout Madagascar. Antimalarials are essential for all visits.
Is tap water safe in Madagascar?
No. Do not drink tap water. Use bottled water throughout.
What healthcare is available in Madagascar?
Medical facilities are very limited outside Antananarivo. Medical evacuation cover is essential.

Data based on WHO International Travel and Health and CDC Yellow Book 2026. Last verified: April 2026. Always verify current requirements with a travel health clinic before departure.