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East Africa
🇲🇬 Vaccines for Madagascar
Entry requirements and CDC/WHO recommendations for travel to Madagascar.
No Yellow Fever requirement unless arriving from an endemic country. Malaria is present throughout the island — prophylaxis is essential. Two things that set Madagascar apart: plague is genuinely present here, at higher rates than almost anywhere in the world — avoid contact with rodents and fleas. Rabies is also a concern.
Medical disclaimer: This is general information only — not personal medical advice. Requirements and risks change. Always consult a qualified travel health clinic before departure.
Required for entry
No vaccines required for entry to this destination.
Recommended by CDC / WHO
Hepatitis A
Food and water contamination risk.
💉 2 doses
📅 Book at least 4 weeks before travel
⚡ Effective: 2 weeks after 1st dose. Full protection after 2nd dose (6–12 months later).
🛡 Protects for: 1st dose ~1 yr. 2nd dose: lifetime.
Recommended
Typhoid
Contaminated food and water.
💉 1 dose
📅 Book at least 3 weeks before travel
⚡ Effective: 2 weeks after vaccination.
🛡 Protects for: 3–5 years. Booster recommended if re-exposure.
Recommended
Rabies
Animal bites risk.
💉 3 doses
📅 Book at least 5 weeks before travel
⚡ Effective: After 3rd dose. 2nd dose 7 days after 1st, 3rd dose 21 days after 1st.
🛡 Protects for: Pre-exposure reduces post-bite treatment needed. Boosters based on blood tests.
Recommended
Disease risks
- ⚠Malaria (high risk throughout)
- ⚠Plague (periodic outbreaks — highest in the world)
- ⚠Rabies
- ⚠Cholera (periodic)
Notes: Malaria prophylaxis essential. Madagascar has one of the highest rates of plague in the world — avoid contact with rodents and fleas.
Approximate cost per person
Required vaccines
—
None required for entry
Recommended vaccines
~€522
(~$568)
per person · full courses
Hepatitis A (2 doses)€140 ($152)
Typhoid (1 dose)€45 ($49)
Rabies (3 doses)€273 ($297)
Malaria tablets (4 weeks) (1 dose)€64 ($70)
💡 Approximate figures based on private European travel clinic rates (April 2026). Actual costs vary by clinic and country. Not all recommended vaccines will apply to every trip — discuss your specific itinerary with a travel health clinic.
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Data based on WHO International Travel and Health and CDC Yellow Book 2026. Last verified: April 2026. Always verify current requirements with a travel health clinic before departure.