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🇮🇹 Vaccines for Italy

Entry requirements & recommendations for travel to Italy

No travel-specific vaccines needed for Italy. Hepatitis A is worth considering for rural southern Italy and Sicily. Routine vaccinations should be current. Italy's healthcare quality varies significantly by region — northern Italy is generally excellent, some parts of the south and Sicily have more limited facilities. Tap water is safe throughout. West Nile Virus has been recorded in the Po Valley and parts of northern Italy in recent years, transmitted by mosquitoes — not a major risk for short-term tourists but worth being aware of if you're spending extended time outdoors in affected areas during summer.

Medical disclaimer: This is general information only — not personal medical advice. Requirements and risks change. Always consult a qualified travel health clinic before departure.
Required for entry

No vaccines required for entry to this destination.

Recommended by WHO & CDC

No travel-specific vaccines recommended for most visitors.

Disease risks
  • ⚠No significant travel vaccine risks for most visitors
Often combined with
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Italy's healthcare quality varies significantly by region — northern Italy is generally excellent, some parts of the south and Sicily have more limited facilities. Tap water is safe throughout. West Nile Virus has been recorded in the Po Valley and parts of northern Italy in recent years, transmitted by mosquitoes — not a major risk for short-term tourists but worth being aware of if you're spending extended time outdoors in affected areas during summer.

When to book

Book 2 weeks before if getting Hepatitis A. Italy is low-risk overall.

Common questions
Do I need vaccines for Italy?
No vaccines required for entry. Hepatitis A worth considering for rural southern Italy, Sicily, and Sardinia where hygiene can be more variable.
Is there malaria in Italy?
No. Italy is malaria-free.
Is tap water safe in Italy?
Yes in most areas. Major cities including Rome, Milan, and Florence have excellent water quality. In rural Sicily and southern Italy, many locals prefer bottled water.
What is the main health risk for tourists in Italy?
No significant tropical disease risks. Food and wine are the main health considerations in Italy — in a positive sense.

Data based on WHO International Travel and Health and CDC Yellow Book 2026. Last verified: April 2026. Always verify current requirements with a travel health clinic before departure.